Department of Biological Sciences

Anti-bacterial Barrier cream
A highly effective barrier cream/powder has been researched by the University of Lincoln, to help protect against environmental contaminants. This may be of particular use to animals susceptible to for example Mud Fever or MRSA infections.

It has been shown to have anti-bacterial and anti-fungal properties with no known side effects. Some indirect evidence indicates haemostatic and wound healing properties.

The cream is based on the anti-microbial properties of silver. Though this is an ancient practice, in this instance atomic silver rather than an ionic silver is used. This maximises the safety of using silver when applied to the skin.
In addition the silver is strongly bound to an inert carrier (Chitosan). This further increases the safety of silver but also gives the cream potential wound-healing properties. Together they are an effective barrier against a wide range of micro-organisms. No evidence has yet been found of resistance development against the active ingredient.

Just a few of the organisms it has been shown to be effective against:
Dermatophilus congolensis
(Mudfever)
Malassezia pachydermatis
Staphylococcus aureus
(including MRSA)
Pseudomonas aeroginosa

MRSA-inhibition1A ------------ BMRSA-inhibition2
A) Inhibition by wound cream of MRSA (right, bottom) in-vitro, compared to controls (top, left)
B) Inhibition by wound powder of Pseudomonas aeroginosa (left) in-vitro, compared to control (right)

The cream has been designed to be applied to:

  • intact skin
  • any superficial skin infections, minor cuts and abrasions
  • hand or skin as anti-bacterial/fungal barrier cream (e.g. for use in barrier nursing)

A powder version has been designed to be applied to:

  • weeping/wet skin
  • weeping/wet superficial skin infections, minor cuts and abbrasions
  • sites where application of the cream is difficult or impractical

    Eventually these products are intended to be be used by vets, veterinary nurses or pet owners at home.

More formal research results will be published on this site. Having successfully tested the anti-microbial efficacy in-vitro, extension to field studies are now planned.
Currently field studies to test the efficacy of the barrier creams against environmental contaminants are ongoing. Any one interested in participating please go to www.lincoln.ac.uk/dbs/researchprojects-participate for more information.

Results field trial (sample)


Field trial results, using anti-microbial barrier powder and cream on mud fever infections on an equine distal limb. A) pre-application; B) after 1 week of application; C) after 3 weeks of application

More background information

Other studies:

 

 

Department of Biological Sciences

University of Lincoln

Riseholme Park

Riseholme

Lincoln

LN2 2LG

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